'Burnout 'causes total lessening o f a person's both physical and mental resources caused by excessive and prolonged level ofjob stress thereby affects their job performance. Many job related characters such as role conflict and role ambiguity are related to burnout. While many empirical studies are done on the employees 'burnt out at international level, in India we have one authentic study by Sharma. The study analyses the effects o f burnout in four dimensional aspects such as stress personality, organisational role stress, emotional intelligence, personal effectiveness and adjustments. The present study has adapted and operationalises sharma's model and looks into one o f the dimensional aspects o f burnout namely 'organisational role stresses'. this study has taken random sample o f 175 employees o f thirty six years from a leading Pharmaceutical sector. Using regression Analysis and Anova test on various predictors such as role ambiguity, resources inadequacy, inter-role distance, role isolation and personal inadequacies are able to explain the phenomenon o f burnt out significantly. Among them ‘role ambiguity ’ appears to high contributor to the process o f burnout o f the employees. There is lack o f clarity or poor understanding about the role o f executives which creates stress and thereby the burnout. The study concludes that burnout is an important issue in the pharmaceutical industry, especially among the middle level executives.